FAQ: How fast does Seachem Prime® work?

Prime® removes chlorine and chloramine almost instantly upon being added to water, and will immediately detoxify ammonia, nitrite, and nitrate.  The chlorine and chloramine is permanently removed (they are broken down into a form that will not re-associate in water) and the ammonia, nitrite, and nitrate detoxification lasts for 48 hours.  If you are dosing Prime® specifically to detoxify ammonia or nitrite, you should re-dose Prime® every 48 hours until the bacteria colonies in the tank are large and stable enough to consume these chemicals.