FAQ: How long does Seachem Prime® stay bound to the ammonia, nitrite, and nitrates?

Prime® will bind up those compounds for up to 48 hours. If they are still present after that time frame, they are released back into the water, unless Prime® is re-dosed accordingly. Also, if your ammonia or nitrite levels are increasing within a 24-hour period, Prime® can be re-dosed every 24 hours.