Yes! To the best of our knowledge, there are no fish, invertebrates, or plants that have a specific aversion to Prime®. However, "Prime® Tolerant" is not the same as "Water Change Tolerant". Many fish, plants, and invertebrates are stressed by sudden high-percentage water changes. For standard community tanks, we recommend water changes of 30% of the tank or less, and for more sensitive tank inhabitants, we recommend no more than 20% of the tank at a time.
Prime® Compatibility Guide
Green: This product is safe for these tank inhabitants. Take care to avoid sudden large shifts in water parameters within the tank, and review the dosing instructions carefully to avoid improper dosing.
Orange: These tank inhabitants are more sensitive, and while the product can still be used on them, it's best to start with a partial dose and work up to the full dose over time
Red: This product is either notably stressful or utterly unsuitable for these tank inhabitants. It would be best to opt for a different product if possible. Click tank inhabitant name for alternate products.
Black: There should never be any need to use this product in a tank with these tank inhabitants - we have no data as to compatibility for this reason. Click the tank inhabitant name for alternate products.
| Freshwater Community Fish | Saltwater Community Fish | Scale-less fish |
| Sharks | Rays | Eels |
| Freshwater Sharks | Freshwater Rays | Freshwater Eels |
| Loaches | Catfish | Aquatic Frogs |
| Shrimp | Snails | Clams |
| Plants | Corals | Exotic Invertebrates |
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