FAQ: Can I use Seachem Purigen® together with ________?

Another Company's product

There are a lot of aquarium products on the market, and while most of them will work perfectly fine together in the aquarium, some will not.  We can't 100% guarantee any product that's not our own, but here's a few quick rules:

  1. Avoid using products that overlap in function.  Either one works and so it's the one you should be using, both work and so it's a waste to use them both, or neither work and you should be looking for a third, better product. In the case of organics-absorbing media like Purigen®, while an overdose is not harmful to the system, there is a point at which adding more of this type of media is not helpful to the system.
  2. Research the products you use carefully.  Purigen® can be used alongside most supplements and types of filtration media, but is capable of removing some types of medication from the water.  Purigen® should not be used alongside medications for this reason.  In addition, some supplements are designed to "stain" the water of an aquarium.  Purigen® is very effective at removing this type of discoloration.
  3. When in doubt, pull the filter media.  Purigen® can be stored more-or-less indefinitely in a sealed container as long as it is kept wet.  If you are unsure if Purigen® and the other product will interact, it is perfectly fine to remove the Purigen® and store it for later.
  4. Filter medias generally do not interact.  It is rare to find filter medias that direct interact with each other. Know what your filter medias are intended to do, and choose filter medias that accomplish your goals in the aquarium.

Seachem® Products

It is safe to use Purigen® alongside most Seachem® products except for medications, which should never be used with any type of chemical filter media (carbon, phosphate absorbers, etc).  It is also worth noting that Purigen® and other organics-absorbing medias are very effective at reducing the nitrate production in an aquarium by absorbing organic waste.  If you intend to maximize nitrate production to help feed photosynthetic organisms, we would recommend to hold off on the Purigen®.


Green: There is no interaction between this product and Purigen®

Blue: While Purigen® may be able to absorb components of this product under laboratory conditions, there is typically no impact on the product or the Purigen® under aquarium conditions.  It is considered perfectly fine to use these products together.

Red: Purigen® will directly absorb components of this product, and they should not be used together.

Black: There are no circumstances under which it would be recommended to use these products together in the same tank, so even though they do not interact, it is not recommended to use them together.

Plant Products

Flourish® Flourish Excel™ Flourish Iron™ Flourish Nitrogen™
Flourish Phosphorous™ Flourish Potassium™ Flourish Trace™ Flourish Advance®
Flourish Tabs™ Alkaline Buffer™ Acid Buffer™ Equilibrium™


Water Conditioners

AmGuard™ Clarity® HeadStart Pack™ Prime®
Pristine™ Safe® Stability® StressGuard™


Freshwater Buffers & Supplements

Acid Regulator™ Alkaline Regulator™ American Cichlid Salt™ Arowana Buffer™
Betta Basics™ Brackish Salt™ Cichlid Lake Salt™ Cichlid Trace™
Discus Buffer® Discus Trace™ Fresh Trace™ Gold Basics™
Gold Buffer™ Gold Salt™ Gold Trace™ Malawi/Victoria Buffer™
Neutral Regulator® Liquid Neutral Regulator® Tanganyika Buffer™  


Filter Medias

CupriSorb™ de*nitrate™ HyperSorb™ Matrix™
MatrixCarbon™ PhosBond™ PhosGuard™ PhosNet™
ZeoLite™ Renew™ SeaGel™




Do not use Purigen in a tank that is currently being dosed with medication - it has the potential to remove the medication.  

However, it is perfectly fine to use a Purigen® in a tank being treated with a medicated food blend.  We recommend:

MetroPlex™ Food Blend for internal and external parasites like ich, velvet, and hexamita

KanaPlex™ Food Blend for internal and external bacterial and fungal infections

NeoPlex™ Food Blend for bacterial infections of the intestines

SulfaPlex™ Food Blend for external bacterial infections

Cupramine™ Focus™ KanaPlex™ MetroPlex™
NeoPlex™ ParaGuard™ PolyGuard™ SulfaPlex™


Saltwater Supplements

Marine buffer® Liquid Marine Buffer® Marine Trace™ Reef Adv Calcium™
Reef Adv Magnesium™ Reef Adv Strontium™

Reef Buffer™

Reef Builder™
Reef Calcium™ Reef Carbonate™ Reef Complete® Reef Dip™
Reef Fusion 1™ Reef Fusion 2™ Reef Kalkwasser™ Reef Pack Enhancer™
Reef Pack Fundamentals™ Reef Phytoplankton™ Reef Plus™ Reef Reactor™ Lg
Reef Reactor™ Md Reef Strontium™ Reef Trace™ Reef Zooplankton™
VibrantSea® Reef Iodide™    


 aquavitro® Supplements

activate™ synthesis™ carbonate™ envy™
mineralize™ premier™ propel™ seed™
remediation™ alpha® balance™ calcification™
eight.four™ fuel™ ions™ vibrance™


 aquavitro® Filter Medias

phosfiltrum™ purfiltrum™ biogen®  
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