NOT RECOMMENDED.
These medications do not interact in the water, but PolyGuard™ already treats external bacterial infections, so there is no need to use it together with NeoPlex™. Using both medications at once is more likely to stress the fish than it is to help them. We recommend to finish the course of one of the antibiotics and the switch to the other if necessary.
For more information about using the Seachem® medications together, check out FAQ: Can I use the Seachem® medications together?
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