PROCEED WITH CAUTION.
Seachem® never recommends using multiple medications if it is possible to treat the fish with only one. Broad-spectrum medications like ParaGuard™ and PolyGuard™ are capable of treating external bacterial and parasitic infections simultaneously, so if possible one of these should be used to treat a fish with both a bacterial and parasitic infection.
That said, if a fish simultaneously has an internal parasitic infection (hexamita, worms, etc.) and an external bacterial infection (lesions, septicemia, fin rot, etc.), or if a fish develops a severe bacterial infection after a treatment with MetroPlex™ has been started, it is possible to use SulfaPlex™ in the water and MetroPlex™ in the fish's food to clear out the infections.
For more information about using the Seachem® medications together, check out FAQ: Can I use the Seachem® medications together?
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