Matrix™ is best when you want a multi-purpose filter media to house both aerobic and anaerobic bacteria or when you cannot set up a filter with a flow rate of less than 50 gallons per hour. It will remove nitrate, but not as much nitrate as de*nitrate™ can. de*nitrate is better when you specifically want to remove nitrate and you already have plenty of biomedia for aerobic bacteria.
FAQ: Should I use Seachem Matrix™ or de*nitrate™? It seems like they both remove nitrate.
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