Only certain slime coat products will cause Purigen® to become toxic; the products that do this are amine based. Prime® and Safe® are not amine based and so will not cause this problem. If you're curious, what happens is that the amine compounds can strongly bind to the resin, then when they (the amines) come into contact with any chlorine they will form chloramines which are highly toxic. We offer a stress coat product, StressGuard™, which is not amine based and so can be used in conjunction with Purigen®.
FAQ: Which products will foul Seachem Purigen®?
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